Analytical Data
-
基因名
VGLL4
- Application
-
别名
VGLL4; KIAA0121; Transcription cofactor vestigial-like Protein 4; Vgl-4
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q14135
-
表达区间
1-290 aa
-
氨基酸序列
METPLDVLSR AASLVHADDE KREAALRGEP RMQTLPVASA LSSHRTGPPP ISPSKRKFSM EPGDEDLDCD NDHVSKMSRI FNPHLNKTAN GDCRRDPRER SRSPIERAVA PTMSLHGSHL YTSLPSLGLE QPLALTKNSL DASRPAGLSP TLTPGERQQN RPSVITCASA GARNCNLSHC PIAHSGCAAP GPASYRRPPS AATTCDPVVE EHFRRSLGKN YKEPEPAPNS VSITGSVDDH FAKALGDTWL QIKAAKDGAS SSPESASRRG QPASPSAHMV SHSHSPSVVS
-
分子量
30.9 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
VGLL4 (Vestigial-like 4) is a transcriptional co-regulator that plays a critical role in various biological processes, including cellular proliferation, differentiation, and apoptosis. Its involvement in the Hippo signaling pathway, which regulates organ size and tissue homeostasis, positions VGLL4 as a significant player in cancer biology and tissue regeneration. Research into VGLL4 has gained momentum due to its dual role in promoting tumor suppression and enhancing tissue repair mechanisms. Aberrant expression of VGLL4 has been implicated in several types of cancer, where it can function as a tumor suppressor by inhibiting oncogenic signals. Conversely, it may also contribute to cell survival and proliferation under certain conditions. The study of VGLL4 recombinant proteins aims to elucidate its molecular mechanisms and interactions with other proteins in signaling pathways. Understanding these dynamics could unveil potential therapeutic targets for cancer treatment and strategies for tissue engineering. As researchers investigate VGLL4's structure and function, recombinant protein production becomes essential for functional assays, drug screening, and characterizing its regulatory networks, thereby contributing to a deeper understanding of its role in both cancer and regenerative medicine.
