Analytical Data
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Gene name
FOXR1
- Application
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Alternative Names
FOXR1; FOXN5; DLNB13Forkhead box protein R1; Forkhead box protein N5
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6PIV2
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Expression Region
1-292aa
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AA Sequence
MGNELFLAFT TSHLPLAEQK LARYKLRIVK PPKLPLEKKP NPDKDGPDYE PNLWMWVNPN IVYPPGKLEV SGRRKREDLT STLPSSQPPQ KEEDASCSEA AGVESLSQSS SKRSPPRKRF AFSPSTWELT EEEEAEDQED SSSMALPSPH KRAPLQSRRL RQASSQAGRL WSRPPLNYFH LIALALRNSS PCGLNVQQIY SFTRKHFPFF RTAPEGWKNT VRHNLCFRDS FEKVPVSMQG GASTRPRSCL WKLTEEGHRR FAEEARALAS TRLESIQQCM SQPDVMPFLF DL
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Molecular Weight
33.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FOXR1, a member of the Forkhead box (Fox) transcription factor family, plays a pivotal role in various biological processes, including developmental regulation and cellular differentiation. Initial studies have identified FOXR1 as a critical factor involved in the development of the central nervous system and immune response. Its expression patterns are notably observed in neural tissues, suggesting a role in neurogenesis and neural patterning. Dysregulation of FOXR1 has been implicated in various pathologies, including cancers and neurological disorders, highlighting its potential as a therapeutic target. Recent advancements in protein engineering have facilitated the production of recombinant FOXR1, which enables detailed functional assays and structural characterizations. Research focusing on the biophysical properties of FOXR1, as well as its interactions with other proteins and DNA, is crucial for understanding its mechanism of action and regulatory roles in cellular processes. Furthermore, the development of FOXR1-based assays could pave the way for novel diagnostic and therapeutic approaches in disease contexts where FOXR1 is implicated. Overall, the study of FOXR1 recombinant protein is essential for unraveling the complexities of its functions and contributions to health and disease.
