Analytical Data
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基因名
TBXAS1
- Application
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别名
TBXAS1; CYP5; CYP5A1; TXAS; Thromboxane-A synthase; TXA synthase; TXS; Cytochrome P450 5A1; Hydroperoxy icosatetraenoate dehydratase
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P24557
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表达区间
357-533aa
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分子量
24kda
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Identification
Protein Description
TBXAS1 (Thromboxane A Synthase 1) is an enzyme that plays a pivotal role in the biosynthesis of thromboxane A2, a potent vasoconstrictor and platelet aggregator. It is primarily found in vascular tissues and platelets, where it contributes significantly to cardiovascular homeostasis and the regulation of hemostasis. The dysregulation of TBXAS1 has been implicated in various pathological conditions, including cardiovascular diseases, hypertension, and thromboembolic disorders. As research progresses, understanding the structure-function relationship of TBXAS1 and its interaction with other molecular players in the thromboxane pathway has gained importance. Recombinant TBXAS1 protein production enables detailed biochemical and biophysical studies, facilitating insights into its enzymatic mechanisms and potential inhibitors. These studies are crucial for developing therapeutic strategies aimed at modulating thromboxane A2 levels in disease states. Moreover, recombinant TBXAS1 serves as a valuable tool for high-throughput screening of compounds that may have anti-thrombotic effects. This research area continues to evolve, with the goal of elucidating the role of TBXAS1 in health and disease, ultimately contributing to improved cardiovascular therapies and patient outcomes.












