Recombinant Mouse CD147 Protein(HEK293), His

CD147, also known as basigin or extracellular matrix metalloproteinase inducer (EMMPRIN), is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. It plays a crucial role in various physiological and pathological processes, including cell proliferation, differentiation, and migration, primarily through its interaction with integrins and other proteins in the extracellular matrix. Research has increasingly focused on CD147 due to its implications in cancer progression, cardiovascular diseases, and inflammatory responses. In particular, CD147 is implicated in promoting tumor progression by enhancing matrix metalloproteinase (MMP) activity, facilitating tumor invasiveness and metastasis. The generation of recombinant CD147 proteins has emerged as a valuable tool for elucidating its functional roles and interactions in these processes. By producing CD147 in a controlled environment, researchers can investigate its structure-function relationships, binding properties, and potential as a therapeutic target. Furthermore, recombinant CD147 can be used in the development of diagnostic assays or targeted drug delivery systems, making it a focal point in both basic and translational research. Understanding CD147's mechanisms may pave the way for novel therapeutic strategies aimed at inhibiting its function in diseases characterized by aberrant cell signaling and extracellular matrix remodeling. Thus, the study of CD147 recombinant proteins not only enhances our comprehension of its biological significance but also contributes to the development of innovative approaches to tackle various diseases.