Recombinant Rat BCMA/TNFRSF17 Protein(HEK293), hFc

BCMA/TNFRSF17

B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells[1]. BCMA/TNFRSF17 Protein, Rat (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 49 amino acids (M1-T49) and is produced in HEK293 cells.

SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

Measured by its binding ability in a functional ELISA. When Recombinant Mouse BAFF Protein is immobilized at 10 µg/mL (100 µL/well) can bind Biotinylated Recombinant Rat BCMA/TNFRSF17. The ED50 for this effect is 0.05989 μg/mL. Measured by its binding ability in a functional ELISA. When Recombinant Mouse BAFF Protein is immobilized at 10 µg/mL (100 µL/well) can bind Biotinylated Recombinant Rat BCMA/TNFRSF17. The ED50 for this effect is 0.05989 μg/mL.

Tumor necrosis factor receptor superfamily member 17; CD269; TNFRSF17; BCM; BCMA

Rat

HEK293

N-hFc

Greater than 90% as determined by SDS-PAGE.

D3ZKQ8

M1-T49

Partial

40 kDa

< 1.0 EU per μg protein as determined by the LAL method.

Freeze-dried powder

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.