Analytical Data
-
基因名
IL-16
- Application
-
别名
LCF; PrIL-16; Lymphocyte Chemoattractant Factor; Pro-Interleukin 16
-
种属
Bovine
-
表达系统
E. coli
-
标签
N-His
-
纯度
> 97% as determined by SDS-PAGE.
-
蛋白编号
Q0V8R5
-
表达区间
Ser508~Pro627
-
分子量
16kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IL-16, a cytokine initially identified as a chemoattractant for CD4+ T cells, plays a significant role in immune regulation and inflammation. It is primarily produced by various immune cells, including CD8+ T cells, dendritic cells, and certain epithelial cells, and it functions through its receptor, CD4, initiating several signaling pathways that affect T cell proliferation and activity. Research on IL-16 has intensified due to its involvement in various inflammatory diseases, including asthma, rheumatoid arthritis, and multiple sclerosis, where it can exacerbate immune responses. The role of IL-16 as an immunomodulator suggests potential therapeutic applications in managing autoimmune diseases and conditions characterized by chronic inflammation. The development of recombinant IL-16 protein has enabled researchers to study its biological functions in vitro and in vivo, providing insights into its mechanisms of action and potential for therapeutic targeting. By examining the effects of IL-16 on immune cell behavior and its interaction with other cytokines, scientists aim to uncover the pathways through which IL-16 influences immune responses, thereby contributing to the development of novel treatment strategies. Understanding IL-16's multifaceted role in the immune system is crucial for elucidating its potential as a biomarker for disease progression and a target for therapeutic intervention, paving the way for advancements in precision medicine for inflammatory disorders.
