Analytical Data
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Gene name
AIF1
- Application
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Alternative Names
Aif1; Iba1Allograft inflammatory factor 1; AIF-1; Ionized calcium-binding adapter molecule 1
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Species
Mouse
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Source
E. coli
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Tag
N-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O70200
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Expression Region
S2-P147
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Protein Length
Full Length of Mature Protein
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AIF1, or Apoptosis-Inducing Factor 1, is a protein known for its role in mediating apoptosis and cellular stress responses. Research into AIF1 recombinant protein has gained significant traction due to its involvement in various pathological conditions, including neurodegenerative diseases, cancers, and inflammatory disorders. AIF1 is predominantly expressed in immune cells, where it plays a crucial role in modulating inflammatory responses and cell survival. Its involvement in apoptosis and the mitochondrial pathway has made it a target of interest for therapeutic strategies aimed at regulating cell death and survival in disease contexts. The recombinant form of AIF1 enables researchers to thoroughly investigate its functional properties and potential interactions with other cellular molecules. Additionally, the ability to produce AIF1 in a controlled environment allows for enhanced studies into its structure-function relationship, facilitating the development of drugs that can either mimic or inhibit its action, depending on the therapeutic need. Furthermore, the study of AIF1 has implications in understanding the broader mechanisms of cell death and inflammatory processes, potentially leading to novel interventions for diseases characterized by dysregulated apoptosis or inflammation. Overall, the research surrounding AIF1 recombinant proteins is pivotal for elucidating its biological functions and designing targeted therapies for various acute and chronic diseases.
