Cat: IPD-X27892

Recombinant Mouse AIF1 Protein,His

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Analytical Data

  • 基因名

    AIF1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Aif1; Iba1Allograft inflammatory factor 1; AIF-1; Ionized calcium-binding adapter molecule 1

  • 种属

    Mouse

  • 表达系统

    E. coli

  • 标签

    N-6*His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O70200

  • 表达区间

    S2-P147

  • 蛋白长度

    Full Length of Mature Protein

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

AIF1, or Apoptosis-Inducing Factor 1, is a protein known for its role in mediating apoptosis and cellular stress responses. Research into AIF1 recombinant protein has gained significant traction due to its involvement in various pathological conditions, including neurodegenerative diseases, cancers, and inflammatory disorders. AIF1 is predominantly expressed in immune cells, where it plays a crucial role in modulating inflammatory responses and cell survival. Its involvement in apoptosis and the mitochondrial pathway has made it a target of interest for therapeutic strategies aimed at regulating cell death and survival in disease contexts. The recombinant form of AIF1 enables researchers to thoroughly investigate its functional properties and potential interactions with other cellular molecules. Additionally, the ability to produce AIF1 in a controlled environment allows for enhanced studies into its structure-function relationship, facilitating the development of drugs that can either mimic or inhibit its action, depending on the therapeutic need. Furthermore, the study of AIF1 has implications in understanding the broader mechanisms of cell death and inflammatory processes, potentially leading to novel interventions for diseases characterized by dysregulated apoptosis or inflammation. Overall, the research surrounding AIF1 recombinant proteins is pivotal for elucidating its biological functions and designing targeted therapies for various acute and chronic diseases.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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