Cat: IPD-X23539

Recombinant Dog Clusterin/APOJ Protein,His

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Analytical Data

  • 基因名

    Clusterin/APOJ

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CLU; TRPM2; KUB1; CLI; APOJ; SGP2; AAG4; APO-J; SP-40; Apolipoprotein J; Complement Lysis Inhibitor; 40,Sulfated Glycoprotein 2; Testosterone-Repressed Prostate Message 2

  • 种属

    Dog

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P25473

  • 表达区间

    Asn227~Glu445

  • 分子量

    30kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Clusterin, also known as ApoJ, is a multifunctional glycoprotein that plays crucial roles in various physiological and pathological processes, including lipid metabolism, inflammation, and apoptosis. Initially identified in the context of cardiovascular diseases and neurodegenerative disorders, Clusterin has garnered attention due to its involvement in the clearance of cellular debris and amyloidogenesis, particularly in Alzheimer's disease. Research has highlighted its protective role in cellular stress responses, making Clusterin a potential biomarker and therapeutic target. The recombinant production of Clusterin/APOJ allows for detailed studies of its structural and functional properties, enabling researchers to explore its mechanisms of action in different biological contexts. Understanding the implications of Clusterin in disease processes can lead to novel strategies for diagnosis and treatment, particularly in conditions characterized by protein misfolding and chronic inflammation. Significantly, advancements in recombinant biotechnology have facilitated the large-scale production of this protein, providing a valuable tool for investigating its interactions, signaling pathways, and potential roles in therapeutic interventions. As such, ongoing studies on the functional attributes of Clusterin/APOJ promise to shed light on its therapeutic potential and its significance in a variety of diseases.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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