Analytical Data
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Gene name
ANGPTL8/Angiopoietin-like 8
- Application
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Alternative Names
RIFL; TD26; C19orf80; Lipasin; Betatrophin; Hepatocellular Carcinoma-Associated Protein TD26
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8R1L8
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Expression Region
Val16~Ala198
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Protein Length
Partial
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Molecular Weight
24kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ANGPTL8 (Angiopoietin-like 8) is a member of the angiopoietin-like protein family, which plays a critical role in regulating lipid metabolism, glucose homeostasis, and energy expenditure. Research has shown that ANGPTL8 acts as a crucial mediator of the effects of insulin and is significantly involved in the regulation of triglyceride levels by inhibiting lipoprotein lipase (LPL) activity. This modulation is particularly important in the context of obesity and metabolic disorders, as elevated ANGPTL8 levels have been associated with insulin resistance and increased risk of cardiovascular diseases. The recombinant protein form of ANGPTL8 has become a focus of scientific investigation, aiming to explore its biological functions and therapeutic potential. Studies utilizing recombinant ANGPTL8 can help elucidate its mechanistic pathways and interactions with other metabolic regulators. Moreover, understanding its role in lipid metabolism might offer novel insights for developing targeted therapies for metabolic syndromes, including type 2 diabetes and dyslipidemia. Consequently, the characterization and functional analysis of recombinant ANGPTL8 are essential for advancing our knowledge of its physiological significance and potential as a biomarker or therapeutic target in metabolic diseases.
