Analytical Data
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Gene name
SEZ6L2//BSRP-A
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简介
The SEZ6L2//BSRP-A protein is a contributor to specialized endoplasmic reticulum function in neurons, implying a unique role in coordinating specific cellular activities. Its identification demonstrates potential effects on the regulation and maintenance of neuronal function, emphasizing its importance in neuronal cellular processes. SEZ6L2//BSRP-A Protein, Mouse (HEK293, His) is the recombinant mouse-derived SEZ6L2//BSRP-A protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
BSRP-A; PSK-1; SEZ6L2; UNQ1903/PRO4349
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Species
Mouse
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Source
HEK293
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Tag
C-8*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q4V9Z5-1
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Expression Region
L28-N844
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Protein Length
Extracellular Domain
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Molecular Weight
115-140 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SEZ6L2/BSRP-A is a protein that has garnered attention due to its potential roles in neurodevelopmental processes and synaptic function. It is part of the SEZ6 family, which is involved in regulating neuronal differentiation and the development of the nervous system. Research has indicated that SEZ6L2 may influence synaptic plasticity, a fundamental mechanism underlying learning and memory. Disruptions in the functions of proteins like SEZ6L2 have been associated with various neurodevelopmental disorders, including autism spectrum disorders and schizophrenia. As such, understanding the molecular properties and biological functions of SEZ6L2 is crucial for elucidating the mechanisms of these diseases and for identifying potential therapeutic targets. Recent studies have focused on the molecular interactions and signaling pathways involving SEZ6L2, as well as its expression patterns in the brain during different developmental stages. Recombining and characterizing the SEZ6L2 protein can provide deeper insights into its role in neuronal connectivity and synaptic integrity. The ongoing research into SEZ6L2/BSRP-A represents a significant step towards deciphering the complexities of brain development and function, which may ultimately lead to advancements in treating neurodevelopmental disorders.
