Analytical Data
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Gene name
SNCB
- Application
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q16143
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Expression Region
1-134aa
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Molecular Weight
21.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNCB (Synuclein Beta) is a member of the synuclein protein family, which plays a crucial role in various neurobiological processes. It is primarily expressed in the brain and is thought to be involved in neurotransmitter release, synaptic function, and neuronal signaling. Research has indicated that SNCB may also be implicated in neurodegenerative diseases, particularly in the context of Parkinson's disease and other synucleinopathies, where the aggregation of alpha-synuclein is a hallmark feature. As the understanding of SNCB's structure and function evolves, scientists are increasingly focusing on its potential roles in cellular mechanisms and pathology. Significant attention is being directed towards the production and characterization of recombinant SNCB proteins, which facilitate detailed studies on its biochemical properties, interactions with other cellular macromolecules, and its effects on neuronal health. These studies aim to elucidate the protein's specific functions and its contributions to disease processes, potentially identifying new therapeutic targets. The ongoing research into SNCB and its recombinant forms not only enhances the understanding of synucleins in health and disease but also paves the way for developing novel strategies to combat neurodegenerative disorders.
