Cat: IPD-X28332

Recombinant Human p73 alpha Protein (Baculovirus),GST

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Analytical Data

  • 基因名

    p73 alpha

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    P73; p73 alpha Protein; TP73

  • 种属

    Human

  • 表达系统

    Baculovirus

  • 标签

    GST

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O15350-1

  • 表达区间

    M1-H636

  • 蛋白长度

    Full Length of Isoform-1

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

p73 alpha is a member of the p53 family of transcription factors, which plays a crucial role in the regulation of the cell cycle, apoptosis, and DNA repair. Unlike its well-characterized counterpart, p53, p73 has been shown to have both pro-apoptotic and anti-apoptotic functions, depending on the cellular context and the presence of specific isoforms. The study of p73 alpha, particularly its recombinantly expressed protein, has garnered considerable interest due to its potential implications in cancer research. Many tumors exhibit alterations in p53 signaling, leading to the activation of alternative pathways. Research on p73 alpha aims to investigate its role in tumorigenesis, as well as its interactions with other cellular proteins, which could shed light on novel therapeutic strategies. Recent studies have highlighted the significance of p73 alpha in response to various stress signals, suggesting that it may possess unique regulatory mechanisms that could be exploited in cancer treatment. Furthermore, understanding the structure and function of p73 alpha at the molecular level can reveal insights into its activation and transcriptional regulation, thus paving the way for its application in targeted therapies and drug design. As researchers continue to explore the potential of p73 alpha, its study not only contributes to the fundamental understanding of tumor biology but also holds promise for the development of innovative approaches to combat cancers that are resistant to conventional treatments.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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