Analytical Data
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Gene name
RBBP8
- Application
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Alternative Names
CTIP
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Species
Human
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Source
E. coli
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Tag
Strep;His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q99708-1
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Expression Region
S641-G685
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RBBP8, or Retinoblastoma Binding Protein 8, plays a crucial role in DNA repair and cell cycle regulation. Initially identified due to its interaction with the retinoblastoma tumor suppressor protein, RBBP8 has gained attention for its involvement in cellular responses to DNA damage and maintenance of genomic stability. As a key component of several cellular pathways, including those related to cell proliferation and apoptosis, any dysfunction in RBBP8 can contribute to various cancers and developmental disorders. Recent studies have highlighted the significance of RBBP8 in the homologous recombination repair mechanism, particularly in the context of BRCA1 and BRCA2-related breast and ovarian cancers. The ability to study RBBP8 through recombinant protein techniques has paved the way for deeper insights into its structure and function, enabling researchers to explore its potential as a therapeutic target. The generation of RBBP8 recombinant proteins facilitates investigations into its enzymatic activity, interaction with other protein complexes, and effects on DNA repair processes. Ultimately, understanding RBBP8's mechanisms may offer novel avenues for cancer therapy and enhance our comprehension of its role in tumorigenesis.
