Cat: IPD-X29252

Recombinant Human PSG6 Protein (Baculovirus),His

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Analytical Data

  • Gene name

    PSG6

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Pregnancy-specific beta-1-glycoprotein 6; PSBG-6; PSBG-10; CGM3; PSG10; PSG12; PSGGB

  • Species

    Human

  • Source

    Baculovirus

  • Tag

    C-His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q00889-2

  • Expression Region

    Q35-H424

  • Protein Length

    Partial

  • Molecular Weight

    58 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

PSG6, or Pregnancy-Specific Glycoprotein 6, is part of a larger family of glycoproteins that play significant roles during pregnancy. These proteins are synthesized in the placenta and are believed to contribute to various physiological processes such as immune modulation, trophoblast invasion, and fetal development. Research on PSG6 has gained attention due to its potential implications in pregnancy-related disorders and its role in regulating maternal-fetal interactions. In particular, PSG6 has been linked to the suppression of maternal immune responses to protect the developing fetus from rejection, which is crucial given the genetic disparity between the mother and the fetus. Moreover, abnormalities in PSG expression levels have been associated with complications such as preeclampsia, fetal growth restriction, and miscarriage. Investigating the structural and functional characteristics of PSG6, as well as its interactions with other biomolecules, could provide insights into its precise role in placental physiology and pathology. Therefore, ongoing studies aim to elucidate the mechanisms underlying PSG6's function and its potential as a biomarker for monitoring pregnancy health, with the ultimate goal of improving maternal and fetal outcomes in clinical settings.

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