Analytical Data
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基因名
Syntaxin-7
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简介
Syntaxin-7 protein is a central player in protein trafficking and membrane fusion events. It guides proteins from the plasma membrane to early endosomes, facilitates homotypic fusion of endocytic organelles, and mediates transport from early endosomes to late endosomes and lysosomes. Syntaxin-7 Protein, Rat (HEK293, His) is the recombinant rat-derived Syntaxin-7 protein, expressed by HEK293 , with N-His labeled tag.
- Application
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生物活性
Immobilized Rat Syntaxin-7 at 2 μg/mL (100 μL/well) can bind Anti- Syntaxin-7 Antibody, The ED50 for this effect is 0.01394 μg/mL. Immobilized Rat Syntaxin-7 at 2 μg/mL (100 μL/well) can bind Anti- Syntaxin-7 Antibody, The ED50 for this effect is 0.01394 μg/mL.
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别名
STX7; Syntaxin 7; syntaxin-7
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种属
Rat
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表达系统
HEK293
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标签
N-6*His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
O70257
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表达区间
S2-L238
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氨基酸序列
SYTPGIGGDPAQLAQRISSNIQKITQCSAEIQRTLNQLGTPQDTPELRQQLQQEQQYTNQLAKETDKYIKEFGFLPTTPSEQRQRKIQKDRLVAEFTTALTNFQKVQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNFVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVESAEVHVQQANQQLSRAANYQRKSRKTL
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蛋白长度
Partial
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分子量
30 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Syntaxin-7 is a member of theSyntaxin family of proteins, which are integral to the processes of membrane fusion and intracellular trafficking. This protein plays a crucial role in the fusion of late endosomal and lysosomal membranes, facilitating the transport and degradation of various biomolecules. Research into Syntaxin-7 is particularly important due to its involvement in several cellular functions, including nutrient uptake, immune response, and the clearance of cellular debris. Dysregulation of Syntaxin-7 has been implicated in various diseases, including neurodegenerative disorders and certain cancers, highlighting the need for a deeper understanding of its mechanisms. Recombinant Syntaxin-7 protein studies aim to elucidate its structure and functional properties, paving the way for potential therapeutic interventions. By generating and characterizing this protein, researchers can investigate its interactions with other proteins involved in vesicular transport, understand its role in cellular homeostasis, and explore its potential as a target for drug development. The ongoing research on Syntaxin-7 thereby provides insights into fundamental cellular processes and opens avenues for novel therapeutic strategies.
