Analytical Data
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基因名
REG-3 alpha/REG3A
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简介
REG-3 α/REG3A proteins exhibit identical protein-binding, oligosaccharide-binding, and peptidoglycan-binding activities.It negatively regulates keratinocyte differentiation and positively regulates keratinocyte proliferation and wound healing, emphasizing its role in skin-related processes.REG-3 alpha/REG3A Protein, Mouse (HEK293, His) is the recombinant mouse-derived REG-3 alpha/REG3A protein, expressed by HEK293 , with C-His labeled tag.
- Application
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别名
Regenerating islet-derived protein 3-alpha; REG-3-alpha; Lithostathine 3; PAP2
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种属
Mouse
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
NP_035389
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表达区间
E27-Q175
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蛋白长度
Full Length of prolactin_like
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分子量
18 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
REG3 delta, also known as REG3D, is a member of the regenerating gene family, which is primarily expressed in the pancreatic tissue and plays a crucial role in various biological processes, including inflammation, tissue regeneration, and host defense. The protein is known for its bactericidal properties, particularly against Gram-positive bacteria, contributing to the innate immune response. Research on REG3D has gained attention due to its potential implications in the pathogenesis of various diseases, including pancreatitis, where its expression is significantly altered. Furthermore, REG3D has been implicated in the modulation of the intestinal microbiota and the maintenance of gut homeostasis, making it a potential biomarker for gastrointestinal disorders. Studies have also explored the therapeutic potential of REG3D in promoting tissue regeneration and healing, especially in the context of pancreatic repair and inflammation. Understanding the molecular mechanisms and pathways regulated by REG3D could provide valuable insights into new treatment strategies for related conditions. The ongoing investigation into REG3D and its recombinant forms aims to elucidate its functional roles and therapeutic applications in both infectious and inflammatory diseases, highlighting its significance in the fields of immunology and regenerative medicine.
