Analytical Data
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Gene name
REG-3 alpha/REG3A
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简介
REG-3 α/REG3A proteins exhibit identical protein-binding, oligosaccharide-binding, and peptidoglycan-binding activities.It negatively regulates keratinocyte differentiation and positively regulates keratinocyte proliferation and wound healing, emphasizing its role in skin-related processes.REG-3 alpha/REG3A Protein, Mouse (HEK293, His) is the recombinant mouse-derived REG-3 alpha/REG3A protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
Regenerating islet-derived protein 3-alpha; REG-3-alpha; Lithostathine 3; PAP2
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Species
Mouse
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Source
HEK293
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Tag
C-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
NP_035389
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Expression Region
E27-Q175
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Protein Length
Full Length of prolactin_like
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Molecular Weight
18 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
REG3 delta, also known as REG3D, is a member of the regenerating gene family, which is primarily expressed in the pancreatic tissue and plays a crucial role in various biological processes, including inflammation, tissue regeneration, and host defense. The protein is known for its bactericidal properties, particularly against Gram-positive bacteria, contributing to the innate immune response. Research on REG3D has gained attention due to its potential implications in the pathogenesis of various diseases, including pancreatitis, where its expression is significantly altered. Furthermore, REG3D has been implicated in the modulation of the intestinal microbiota and the maintenance of gut homeostasis, making it a potential biomarker for gastrointestinal disorders. Studies have also explored the therapeutic potential of REG3D in promoting tissue regeneration and healing, especially in the context of pancreatic repair and inflammation. Understanding the molecular mechanisms and pathways regulated by REG3D could provide valuable insights into new treatment strategies for related conditions. The ongoing investigation into REG3D and its recombinant forms aims to elucidate its functional roles and therapeutic applications in both infectious and inflammatory diseases, highlighting its significance in the fields of immunology and regenerative medicine.
