Analytical Data
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基因名
XCR1
- Application
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别名
CCXCR1; GPR5; XC-Chemokine Receptor 1; G Protein-Coupled Receptor 5; Lymphotactin Receptor
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9R0M1
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表达区间
Thr244~Tyr322
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分子量
15kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
XCR1, or X-C motif chemokine receptor 1, is a crucial receptor involved in the immune system's response to pathogens and cancer. It is primarily expressed on a subset of dendritic cells known as cross-presenting dendritic cells, which are essential for the activation of CD8+ T cells. Research on XCR1 has gained momentum due to its role in mediating immune responses and its potential implications in immunotherapy and vaccine development. As a chemokine receptor, XCR1 participates in the migration of dendritic cells to lymphoid tissues, enhancing the presentation of antigens derived from extracellular sources. This unique pathway is vital for the generation of cytotoxic T cell responses, particularly against tumors and viral infections. Recombinant XCR1 protein studies aim to elucidate the structural and functional aspects of this receptor, aiding the understanding of its signaling mechanisms and interactions with ligands. Furthermore, characterizing XCR1 through recombinant technologies has implications for developing targeted therapies that can boost immune responses or harness XCR1's function in treating malignancies. The ongoing research not only helps in advancing fundamental immunology but also paves the way for novel therapeutic approaches that could improve the efficacy of current cancer treatments and vaccines.












