Analytical Data
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基因名
RPE
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简介
RPE proteins play a key role in cellular metabolism by catalyzing the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. This enzyme activity is a key step in the non-oxidative phase of the pentose phosphate pathway and promotes the interconversion of pentose phosphates. RPE Protein, Mouse (HEK293, His) is the recombinant mouse-derived RPE protein, expressed by HEK293 , with C-His labeled tag.
- Application
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别名
Ribulose-Phosphate 3-Epimerase; RPE; HUSSY-17
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种属
Mouse
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q8VEE0
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表达区间
M1-R228
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氨基酸序列
MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQDPFFDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEAAQKRSLDR
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蛋白长度
Full Length
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分子量
27 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RPE (Retinal Pigment Epithelium) recombinant proteins have garnered significant attention in recent years due to their potential role in understanding retinal diseases and advancing therapeutic strategies. The RPE is a crucial layer of cells in the retina, responsible for various functions including the support of photoreceptor cells, maintenance of the blood-retinal barrier, and regeneration of visual pigments. Dysfunction or degeneration of RPE cells is implicated in several ocular diseases, such as age-related macular degeneration (AMD) and retinal dystrophies. Research on RPE recombinant proteins aims to elucidate their structural and functional properties, which may lead to innovative treatments. These proteins can be utilized to create bioassays, model retinal diseases, and facilitate drug discovery. By producing and characterizing RPE recombinant proteins, scientists seek to gain deeper insights into the molecular mechanisms underlying retinal pathology, paving the way for regenerative medicine approaches and the development of targeted therapies. The exploration of RPE recombinant proteins not only enhances our understanding of retinal biology but also holds promise for the future of vision restoration and preservation in patients affected by debilitating retinal conditions.
