Analytical Data
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Gene name
ADRbK2
- Application
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Alternative Names
B-ARK2; bARK2; Beta-ARK2; GRK3; G-protein-coupled receptor kinase 3
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P35626
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Expression Region
Phe191~Phe453
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Molecular Weight
34kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ADRbK2, a member of the adrenergic receptor family, is significant in various physiological processes, including cardiovascular regulation, neurotransmission, and metabolic control. Researchers are increasingly interested in recombinant proteins, particularly ADRbK2, due to their potential therapeutic applications in treating heart diseases, hypertension, and metabolic disorders. The ability to produce ADRbK2 in a recombinant form allows for detailed studies of its structure, function, and interaction with ligands and signaling pathways. This is crucial for understanding its role in disease mechanisms and for the development of targeted drugs. Recent advancements in genetic engineering and protein expression systems have facilitated the efficient production of ADRbK2, enabling researchers to investigate the receptor's pharmacological properties and its potential as a drug target. Furthermore, studying ADRbK2’s signaling mechanisms can reveal insights into receptor desensitization and internalization processes, which are essential for the development of novel therapeutic strategies. The exploration of ADRbK2 in a recombinant form not only enhances our comprehension of adrenergic signaling but also paves the way for innovative interventions in related health conditions, emphasizing its significance in biomedical research and drug development.
