Analytical Data
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Gene name
GHSR
- Application
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Alternative Names
GHRP; GH-releasing peptide receptor; Ghrelin receptor
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q92847
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Expression Region
Met1~Arg70
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Molecular Weight
40kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GHSR (Growth Hormone Secretagogue Receptor) is a G-protein-coupled receptor (GPCR) that plays a critical role in regulating growth hormone release and energy homeostasis. Its primary ligand, ghrelin, has gained attention for its involvement in appetite regulation, metabolism, and various physiological processes. Research on GHSR recombinant proteins has advanced significantly, driven by the need to understand ghrelin signaling mechanisms in detail, as well as its potential implications in obesity, diabetes, and other metabolic disorders. With the increasing prevalence of these conditions, elucidating the structure and function of GHSR is crucial. Recombinant GHSR proteins facilitate high-throughput screening of novel compounds, allowing for the identification of GHSR modulators that could serve as therapeutic agents. Additionally, the study of GHSR interactions with different ligands and signaling pathways has provided insights into GPCR functional dynamics, which are vital for drug design. Furthermore, investigating the structural biology of GHSR using techniques like X-ray crystallography and cryo-electron microscopy has enhanced our understanding of receptor activation and ligand binding, paving the way for the development of targeted treatments. Overall, the research surrounding GHSR recombinant proteins is vital for unlocking new therapeutic strategies in metabolic and endocrine disorders.
