Analytical Data
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基因名
RGS3
- Application
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别名
C2PA; PDZ-RGS3; RGP3
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9DC04
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表达区间
Met1~Thr261
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分子量
33kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RGS3 (Regulator of G-protein Signaling 3) is a member of the RGS protein family, which plays a crucial role in the modulation of G-protein-coupled receptor (GPCR) signaling pathways. These pathways are vital for various physiological processes, including cell proliferation, differentiation, and neuronal signaling. RGS3 specifically enhances the GTPase activity of Gα subunits, thereby accelerating the inactivation of G-proteins and terminating the signaling cascade. Studies have indicated that RGS3 is involved in diverse physiological functions and is implicated in pathological conditions such as cancer and cardiovascular diseases. The potential of RGS3 as a therapeutic target has garnered attention, prompting research into its structure-function relationships. Moreover, recombinant RGS3 proteins are essential for in vitro studies, allowing researchers to elucidate its molecular interactions and regulatory mechanisms. Understanding the functional dynamics of RGS3 can provide insights into its role in GPCR signaling and its impact on health and disease, paving the way for novel therapeutic strategies targeting RGS proteins. Consequently, the production and characterization of RGS3 as a recombinant protein are fundamental to advancing our knowledge in cell signaling and developing therapeutic applications.












