Analytical Data
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Gene name
NR1D1
- Application
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Alternative Names
THRA1; EAR1; THRAL; ear-1; hRev; Rev-ErbA Alpha; V-erbA-related protein 1
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P20393
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Expression Region
Met1~Ala325
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Molecular Weight
44kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NR1D1, also known as nuclear receptor subfamily 1 group D member 1, is a transcription factor that plays a crucial role in regulating circadian rhythms and metabolic processes. It is involved in the repression of genes associated with inflammation and circadian regulation, thereby influencing various physiological functions. Recent studies have highlighted its significance in energy homeostasis, lipid metabolism, and the modulation of insulin sensitivity. Additionally, NR1D1 has been implicated in various diseases, including metabolic disorders, cardiovascular diseases, and certain cancers. The recombinant protein of NR1D1 serves as an important tool for elucidating its biological functions, helping researchers understand its role in cellular mechanisms and potential therapeutic applications. By overexpressing NR1D1 in various cell models, scientists can investigate its interactions with other proteins, identify target genes, and assess its impact on metabolic signaling pathways. This research is crucial for developing novel strategies to combat metabolic diseases and circadian rhythm-related disorders, highlighting the potential of NR1D1 as a therapeutic target in the field of endocrinology and metabolism.
