Analytical Data
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基因名
CDK11B
- Application
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别名
CDC2L1; CDK11; PITSLREA; PK58; Cell division cycle 2-like kinase 1; PITSLRE serine/threonine-protein kinase CDC2L1; Galactosyltransferase-associated protein kinase p58/GTA
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P21127
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表达区间
Phe438~Arg724
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分子量
37kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CDK11B (Cyclin-dependent kinase 11B) is a crucial component of the cell cycle regulation and is involved in various cellular processes, including RNA splicing, transcription, and apoptosis. As a member of the cyclin-dependent kinase family, CDK11B plays a vital role in the phosphorylation of serine and threonine residues on target proteins, thus influencing cell cycle progression and gene expression. Research has shown that CDK11B is implicated in several diseases, including cancer, where its dysregulation can lead to uncontrolled cell proliferation. Additionally, it has been recognized for its potential as a therapeutic target, making the understanding of its structure and function increasingly important. The study of CDK11B recombinant proteins allows researchers to investigate its enzymatic activity, interaction with cyclins, and the downstream effects on cellular pathways. By generating CDK11B in a recombinant format, scientists can explore its role in various biological contexts, contributing to better insights into its mechanism of action and opening avenues for novel treatments targeting CDK11B-related pathways in diseases.
