Analytical Data
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基因名
GDF2
- Application
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别名
Bone morphogenetic protein 9 Short name: BMP-9
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种属
Human
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表达系统
Yeast
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UK05
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表达区间
300-429aa
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分子量
16.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The GDF2 (Growth Differentiation Factor 2), a member of the transforming growth factor-beta (TGF-β) superfamily, plays a crucial role in various biological processes, including embryonic development, tissue repair, and hematopoiesis. Notably, GDF2 is involved in the regulation of vascular biology and is essential for the maintenance of vascular homeostasis. Research has shown that GDF2 mediates signaling pathways that influence angiogenesis and the differentiation of endothelial cells, making it a key factor in cardiovascular health. Abnormalities in GDF2 expression have been linked to several pathological conditions, such as pulmonary arterial hypertension and other cardiovascular diseases. Consequently, GDF2 recombinant protein has become a focus of study, as it can serve as a valuable tool for investigating its biological functions and potential therapeutic applications. Studies involving GDF2 recombinant protein aim to elucidate its role in vascular development and disease, assess its potential as a biomarker, and explore its therapeutic implications in restoring normal vascular function. By employing recombinant technology, researchers can produce GDF2 in sufficient quantities for in vitro and in vivo studies, allowing for a better understanding of its signaling mechanisms and effects on vascular biology. As research progresses, GDF2 may emerge as a promising target for innovative therapeutic strategies aimed at addressing cardiovascular disorders and enhancing tissue regeneration.
