Analytical Data
-
Gene name
PANX2
- Application
-
Alternative Names
PX2; hPANX2
-
Species
Mouse
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q6IMP4
-
Expression Region
His2~Lys253
-
Molecular Weight
31kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PANX2 (Pannexin 2) is a member of the pannexin family of proteins, which are integral membrane channels involved in intercellular communication. Research on PANX2 has gained traction due to its diverse biological roles and potential implications in various physiological and pathological processes. It is expressed in several tissues, notably in the brain, where it is implicated in neurodevelopment and neurotransmission. Dysregulation of PANX2 has been associated with several neurological disorders, including epilepsy and Alzheimer's disease. The study of recombinant PANX2 protein is crucial for elucidating its structure-function relationship and understanding its physiological roles. Recombinant proteins allow for controlled experimental conditions, facilitating the investigation of channel activity, permeability, and interaction with other cellular components. Through recombinant expression systems, researchers can produce high yields of PANX2, enabling detailed biochemical and biophysical studies. Additionally, understanding the mechanisms of PANX2 may uncover novel therapeutic targets for diseases linked to its dysfunction. As research continues to expand on the role of PANX2 in cellular signaling and communication, the recombinant protein offers a valuable tool for dissecting its contributions to health and disease.
