Analytical Data
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基因名
PANX2
- Application
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别名
PX2; hPANX2
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6IMP4
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表达区间
His2~Lys253
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分子量
31kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PANX2 (Pannexin 2) is a member of the pannexin family of proteins, which are integral membrane channels involved in intercellular communication. Research on PANX2 has gained traction due to its diverse biological roles and potential implications in various physiological and pathological processes. It is expressed in several tissues, notably in the brain, where it is implicated in neurodevelopment and neurotransmission. Dysregulation of PANX2 has been associated with several neurological disorders, including epilepsy and Alzheimer's disease. The study of recombinant PANX2 protein is crucial for elucidating its structure-function relationship and understanding its physiological roles. Recombinant proteins allow for controlled experimental conditions, facilitating the investigation of channel activity, permeability, and interaction with other cellular components. Through recombinant expression systems, researchers can produce high yields of PANX2, enabling detailed biochemical and biophysical studies. Additionally, understanding the mechanisms of PANX2 may uncover novel therapeutic targets for diseases linked to its dysfunction. As research continues to expand on the role of PANX2 in cellular signaling and communication, the recombinant protein offers a valuable tool for dissecting its contributions to health and disease.












