Analytical Data
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Gene name
PANX3
- Application
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96QZ0
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Expression Region
Met1~Pro392
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Molecular Weight
60kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PANX3 (Pannexin 3) is a member of the pannexin family of proteins, which are integral membrane proteins that form large-pore channels. These channels are involved in various physiological processes, including cell signaling, inflammation, and tissue homeostasis. PANX3 is predominantly expressed in bone tissues, and recent studies have indicated its critical role in the regulation of osteoblast and chondrocyte functions, suggesting its involvement in skeletal development and maintenance. Its dysfunction has been correlated with various bone-related diseases, such as osteoporosis and osteoarthritis. The recombinant expression of PANX3 has gained significant interest in recent years as researchers aim to elucidate its biological functions and regulatory mechanisms. By studying the recombinant protein, scientists can investigate its channel-forming capabilities, interact with other cellular components, and assess its impact on cell behavior. Furthermore, PACN3’s potential as a therapeutic target in bone disorders highlights its importance, prompting the development of assays and models to explore its functional roles. The production of PANX3 as a recombinant protein allows for detailed biochemical and biophysical characterizations, providing insights into its structure-function relationships and paving the way for future therapeutic applications. Understanding PANX3’s molecular mechanisms is crucial for developing innovative strategies to combat bone diseases and improve skeletal health.
