Analytical Data
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基因名
NF2L2
- Application
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别名
NF-E2-related factor 2; NFE2-related factor 2; Nrf2
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种属
Mouse
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表达系统
E. coli
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标签
N-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q60795
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表达区间
M1-N597
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氨基酸序列
MMDLELPPPGLQSQQDMDLIDILWRQDIDLGVSREVFDFSQRQKDYELEKQKKLEKERQEQLQKEQEKAFFAQFQLDEETGEFLPIQPAQHIQTDTSGSASYSQVAHIPKQDALYFEDCMQLLAETFPFVDDHESLALDIPSHAESSVFTAPHQAQSLNSSLEAAMTDLSSIEQDMEQVWQELFSIPELQCLNTENKQLADTTAVPSPEATLTEMDSNYHFYSSISSLEKEVGNCGPHFLHGFEDSFSSILSTDDASQLTSLDSNPTLNTDFGDEFYSAFIAEPSDGGSMPSSAAISQSLSELLDGTIEGCDLSLCKAFNPKHAEGTMEFNDSDSGISLNTSPSRASPEHSVESSIYGDPPPGFSDSEMEELDSAPGSVKQNGPKAQPAHSPGDTVQPLSPAQGHSAPMRESQCENTTKKEVPVSPGHQKAPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVDDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEREKLLREKGENDRNLHLLKRRLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDTKKN
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蛋白长度
Full Length
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分子量
100 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Nuclear factor E2-related factor 2 (Nrf2), also known as NF2L2, is a transcription factor that plays a crucial role in cellular responses to oxidative stress and electrophilic challenge. Its significance stems from its ability to activate protective genes involved in antioxidant defense, detoxification, and cellular repair mechanisms. Recent research indicates that dysregulation of Nrf2 is linked to various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions. The study of Nrf2 and its signaling pathways has garnered considerable attention due to its potential therapeutic implications. Recombinant Nrf2 protein has emerged as a valuable tool in elucidating the mechanisms underlying Nrf2 activation and function. By producing and studying recombinant NF2L2, researchers can explore its interaction with other proteins, its role in gene expression regulation, and its impact on cellular physiology under oxidative stress. This research not only enhances our understanding of Nrf2's biological significance but also opens avenues for the development of novel therapeutic strategies aimed at harnessing its protective benefits in various pathologies. Ultimately, investments in NF2L2 recombinant protein research promise to contribute to innovative approaches in treating diseases associated with oxidative stress and inflammation.
