Analytical Data
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基因名
ANTXR2
- Application
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别名
CMG-2; CMG2; ISH; JHF; Capillary Morphogenesis Protein 2
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P58335
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表达区间
Gln34~Gly318
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分子量
34kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ANTXR2, also known as anthrax toxin receptor 2, is a crucial protein that plays a significant role in cellular activities, particularly in the context of anthrax pathogenesis. It is a member of the tumor necrosis factor receptor superfamily and is implicated in various physiological processes such as cell proliferation, differentiation, and apoptosis. Research on ANTXR2 has gained interest due to its potential involvement in cancer biology, as its expression patterns can be associated with tumor progression and metastasis. Moreover, ANTXR2 serves as a receptor for anthrax toxin, specifically binding to protective antigen and facilitating the entry of lethal factors into host cells. This dual role makes it a target of interest for therapeutic interventions, as blocking this interaction could have implications for anthrax treatment and the development of novel cancer therapies. As such, studies focusing on the structure, function, and signaling pathways of ANTXR2 are essential to understanding its contributions to disease mechanisms. Ongoing research aims to elucidate its roles in various biological contexts, paving the way for potential biotechnological and clinical applications. Understanding ANTXR2 at the molecular level may provide insights into targeted therapies, improving treatment strategies for diseases associated with its dysregulation.












