Analytical Data
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Gene name
OPN5
- Application
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Alternative Names
GPR136; PGR12; TMEM13; Transmembrane Protein 13; Neuropsin; G Protein-Coupled Receptor 136; G-protein coupled receptor PGR12
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6U736
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Expression Region
Met1~Thr181
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Molecular Weight
24kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
OPN5, also known as opsin 5, is a member of the opsin protein family and is notable for its role as a G protein-coupled receptor (GPCR) that responds to light. Discovered in recent years, OPN5 has garnered interest due to its unique ability to absorb near-infrared light, which distinguishes it from other opsins typically responsive to visible light. This characteristic underlines its potential applications in optogenetics, a technique that utilizes light to control cells within living tissue. Research on OPN5 involves the recombinant expression of this protein to study its structure, function, and signaling pathways. Understanding the mechanics of OPN5 could pave the way for innovative therapies and tools in neuroscience and other fields, as it may help in developing advanced strategies for manipulating neural activity with precision. The recombinant production of OPN5 enables a thorough investigation of its biophysical properties and potential for use in light-driven therapeutic modulation of neuronal circuits. Overall, studying OPN5 not only enhances our knowledge of sensory biology but also opens exciting avenues for biotechnological applications.
