Analytical Data
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Gene name
P2RY14
- Application
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Alternative Names
GPR105; P2Y14; P2Y Purinoceptor 14; G Protein-Coupled Receptor 105; UDP-glucose receptor
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15391
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Expression Region
Pro51~Arg303
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Molecular Weight
36kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
P2RY14, a member of the purinergic receptor family, is known to play a crucial role in various physiological processes, including immune response, inflammation, and cellular signaling. Recent studies have highlighted its significance in the tumor microenvironment, where it influences cancer cell behavior and immune cell interaction. The receptor is activated by ATP and other purines, promoting signaling pathways that can lead to cell proliferation or apoptosis, thereby impacting tumor progression. Moreover, P2RY14 has been implicated in several diseases, including autoimmune disorders and fibrosis, making it a potential therapeutic target. The development of recombinant P2RY14 protein facilitates in-depth structural and functional studies, enabling researchers to explore its binding properties, signaling mechanisms, and interactions with other proteins. This research can provide valuable insights into the receptor’s role in health and disease, potentially leading to novel treatment strategies for conditions mediated by purinergic signaling. As a result, understanding P2RY14's function through recombinant protein research could contribute significantly to advancing therapeutic approaches in oncology and immunology.
