Analytical Data
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基因名
LYVE1
- Application
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别名
XLKD1; CRSBP-1; HAR; Extracellular Link Domain Containing 1; Hyaluronic acid receptor; Cell surface retention sequence-binding protein 1
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种属
Mouse
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表达系统
E. coli
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标签
Two N- s, His- & SUMO-
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8BHC0
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表达区间
Ala24~Thr234
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分子量
40kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1) is a type I transmembrane protein predominantly expressed in lymphatic endothelial cells. It plays a crucial role in lymphatic system functions, including fluid homeostasis, immune response modulation, and hyaluronan metabolism. The study of LYVE1 has garnered significant attention due to its potential implications in various physiological and pathological processes, such as cancer metastasis, inflammatory diseases, and lymphatic disorders. Researchers have focused on characterizing LYVE1 and its interactions with hyaluronan, which may provide insights into the mechanisms underlying lymphatic vessel development and function. The recombinant expression of LYVE1 protein is crucial for these studies, as it allows for detailed investigations into its structure, binding properties, and biological roles. Additionally, LYVE1 has emerged as a promising biomarker for lymphatic system-related diseases and a potential target for therapeutic interventions. Understanding the dynamics of LYVE1 through recombinant studies could lead to novel strategies for managing conditions such as lymphedema and cancer spread, thereby enhancing our knowledge of the lymphatic system's contribution to human health and disease.
