Analytical Data
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基因名
JAM-B/CD322
- Application
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别名
Junctional adhesion molecule 2 ;JAM-2Vascular endothelial junction-associated molecule ;VE-JAM; CD322
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P57087
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表达区间
29-238aa
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分子量
27.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
JAM-B (Junctional Adhesion Molecule B) is a member of the JAM family of immunoglobulin-like proteins, primarily expressed in endothelial cells and various immune cells. It plays a crucial role in mediating cell adhesion, facilitating leukocyte transmigration, and maintaining the integrity of blood-brain and blood-tissue barriers. The interaction of JAM-B with CD322, its receptor, is significant in the context of immune response and vascular biology. Research into JAM-B/CD322 recombinant proteins has gained momentum due to their potential implications in inflammatory diseases, cancer metastasis, and tissue repair processes. Understanding the structural and functional properties of these proteins could provide insights into their role in health and disease. Studies have shown that manipulating the JAM-B/CD322 interactions may help modulate immune responses and improve therapeutic strategies for conditions such as autoimmune disorders or tumor progression. The exploration of JAM-B/CD322 recombinant proteins not only aids in elucidating their biological functions but also holds promise for the development of novel biomolecules with therapeutic applications, thus making it a significant focus in molecular biology and translational research.
