Analytical Data
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基因名
CHL1
- Application
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生物活性
Measured in a cell proliferation assay using SH-SY5Y cells. The ED50 for this effect is 0.369 μg/mL, corresponding to a specific activity is 2710.027 Unit/mg, Measured in a cell proliferation assay using SH-SY5Y cells. The ED50 for this effect is 0.369 μg/mL, corresponding to a specific activity is 2710.027 Unit/mg,
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别名
Neural cell adhesion molecule L1-like protein; CHL1; CALL
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种属
Mouse
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表达系统
HEK293
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
XP_017176866
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表达区间
A25-Q1027
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蛋白长度
Partial
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分子量
113-123 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CHL1, or Cell Adhesion Molecule L1, is a member of the immunoglobulin superfamily that plays a critical role in neuronal development and plasticity. It is primarily expressed in the nervous system and is involved in various processes such as axon guidance, neuronal migration, and regeneration. Dysregulation of CHL1 has been linked to several neurodegenerative diseases and psychiatric disorders, making it a significant target for research. The study of recombinant CHL1 protein is essential for understanding its functional mechanisms and the molecular pathways it influences. By producing this protein in a controlled laboratory environment, researchers can investigate the structure-function relationship, analyze CHL1's interactions with other proteins, and explore its potential as a therapeutic target. Furthermore, recombinant CHL1 can be utilized in various assays, including cell adhesion and migration studies, to elucidate its role in cell signaling and communication. This research contributes to a deeper understanding of neuronal development and holds promise for developing strategies to address neurological disorders linked to CHL1 dysfunction.












