Analytical Data
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基因名
FABP7
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简介
FABP7 Protein, Human expresses in E. coliwith a His tag. Fatty Acid-Binding Protein 7 (FABP-7) is one of the subtypes of FABPs and preferentially binds to n-3 and n-9 polyunsaturated fatty acids (PUFAs) such as docosahexaenotic acid (DHA) and oleic acid, respectively. FABP-7 is thought to be an important molecule for cell proliferation in healthy as well as diseased organisms[1].
- Application
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别名
rHuFABP7, His; Fatty Acid-Binding Protein Brain; B-FABP; Brain-Type Fatty Acid-Binding Protein
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种属
Human
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表达系统
E. coli
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15540-1
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表达区间
M1-A132
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蛋白长度
Full Length of Isoform-1
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分子量
16 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Fatty acid-binding protein 7 (FABP7), also known as brain-type FABP, plays a critical role in the transport and metabolism of fatty acids in the central nervous system. It is predominantly expressed in the brain, particularly in astrocytes and neural progenitor cells, where it is involved in neurodevelopment, myelination, and the regulation of neuroinflammation. Dysregulation of FABP7 has been implicated in various neurodegenerative diseases and psychiatric disorders, including Alzheimer's disease, schizophrenia, and depression. Given its significant influence on brain function and potential as a therapeutic target, research has focused on the production and characterization of recombinant FABP7 proteins. These recombinant proteins facilitate the study of FABP7's molecular mechanisms and interactions with fatty acids and other ligands. Furthermore, understanding the structure-function relationship of FABP7 through these studies may offer insights into its role in brain pathology and aid in the development of novel strategies for intervention in related disorders. The precise characterization of FABP7, including its binding affinities and dynamics, is essential for expanding our knowledge and paving the way for therapeutic innovations targeting this important protein in neurological health and disease.
