Analytical Data
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Gene name
LASP1
- Application
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Alternative Names
Metastatic lymph node gene 50 protein ;MLN 50
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q14847
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Expression Region
1-243aa
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Molecular Weight
54.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LASP1 ( LIM and SH3 protein 1) is a member of the LASP protein family, which plays a crucial role in cell adhesion, motility, and signaling processes. Research has highlighted that LASP1 is involved in various cellular functions, including cytoskeletal dynamics and transcriptional regulation. The protein is particularly notable for its overexpression in several cancers, such as breast, colon, and lung cancers, making it a potential biomarker for aggressive tumor behavior. Studies have demonstrated that LASP1 interacts with actin filaments and various signaling molecules, which suggests its importance in maintaining cellular architecture and responsiveness to external stimuli. Changes in LASP1 expression levels can significantly affect tumor progression and metastasis. As a result, the investigation of recombinant LASP1 protein is essential for understanding its structure-function relationships and the precise mechanisms by which it influences cancer pathways. Furthermore, the production of recombinant LASP1 allows for the exploration of its interactions with other cellular proteins and potential therapeutic applications, including targeted cancer therapies. Enhanced understanding of LASP1's role in pathophysiology could pave the way for novel diagnostic and treatment strategies in oncology. Thus, ongoing research into LASP1, particularly through recombinant protein studies, is vital for elucidating its functions in both normal cellular physiology and pathological conditions.
