Analytical Data
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Gene name
TMC5
- Application
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6UXY8
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Expression Region
Met1~Ala210
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Molecular Weight
30kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TMC5, or Transmembrane Channel-like 5, is a protein that plays a crucial role in cellular processes, particularly in the context of viral infections and immune responses. Recent studies have highlighted its significant involvement in the life cycle of various viruses, including its potential role as a receptor facilitating viral entry into host cells. The interest in TMC5 has surged due to its dual functions, both as a channel involved in ion transport and as a mediator in cellular signaling pathways. Understanding the mechanisms by which TMC5 interacts with viral components may provide insights into the development of novel therapeutic strategies against viral diseases. The recombinant expression of TMC5 in various systems allows researchers to study its structural properties and functional characteristics in detail. Additionally, investigations into post-translational modifications and interactions with other cellular proteins are essential for deciphering its role in pathophysiological contexts. The mounting evidence concerning its implications in immune evasion and host-pathogen interactions frames TMC5 as a pivotal target for drug discovery and vaccine development. As such, research on TMC5 recombinant protein not only enhances our understanding of its biological significance but also opens new avenues for combating viral infections, making it a focal point of current molecular biology and virology studies.
