Analytical Data
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基因名
TP53TG5
- Application
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别名
C20orf10; TP53-inducible gene 5 protein
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y2B4
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表达区间
Tyr190~Thr262
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分子量
40kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TP53TG5, or Tumor Protein P53 Target Gene 5, is a gene that has garnered attention due to its association with the p53 tumor suppressor pathway, which is critical for regulating cell cycle and promoting apoptosis in response to DNA damage. The p53 gene is often referred to as the "guardian of the genome" because of its crucial role in preventing cancer formation. TP53TG5 expression is thought to be regulated by p53, suggesting its potential involvement in cellular stress responses and tumor suppression. Studies indicate that TP53TG5 may function as a pro-apoptotic factor, indicating that it could play a significant role in enhancing the therapeutic efficacy of certain cancer treatments. Research on the recombinant protein of TP53TG5 is essential for elucidating its biological function, interactions with other proteins, and its potential as a therapeutic target. Understanding the mechanisms by which TP53TG5 influences cell signaling pathways and apoptotic processes could provide insights into novel cancer therapies, improve our understanding of p53's multifaceted role in tumor biology, and potentially pave the way towards developing new strategies for overcoming resistance to current cancer treatments. Further investigations into TP53TG5 may lead to the identification of biomarkers for cancer prognosis and treatment response, enhancing personalized medicine approaches in oncology.
