Cat: IPD-X35193

Recombinant Human CEACAM19 Protein (HEK293),His

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Analytical Data

  • Gene name

    CEACAM19

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Biological Activity

    Measured by the ability of the immobilized protein to support the adhesion of the L929 cells. The ED50 for this effect is 0.5232 μg/mL, corresponding to a specific activity is 1.911×103 units/mg. Measured by the ability of the immobilized protein to support the adhesion of the L929 cells. The ED50 for this effect is 0.5232 μg/mL, corresponding to a specific activity is 1.911×103 units/mg.

  • Alternative Names

    Carcinoembryonic antigen-related cell adhesion molecule 19; CEAL1

  • Species

    Human

  • Source

    HEK293

  • Tag

    C-6*His

  • Purity

    Greater than 95% as determined by SDS-PAGE.

  • Uniprot

    Q7Z692-1

  • Expression Region

    A33-G157

  • Protein Length

    Extracellular Domain

  • Molecular Weight

    18-24 kDa.

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CEACAM19 (Carcinoembryonic Antigen-related Cell Adhesion Molecule 19) is a member of the CEACAM family, which plays a crucial role in cell adhesion and immune response regulation. Research into CEACAM19 has gained significance due to its potential implications in various diseases, particularly in cancer. This glycoprotein is primarily expressed in epithelial tissues and has been shown to influence tumor progression and metastasis, making it a target of interest for therapeutic interventions. The understanding of CEACAM19's biological functions and its involvement in signaling pathways could offer insights into tumor biology and help in the development of novel cancer diagnostic and treatment strategies. Recent studies have focused on the production of recombinant CEACAM19 proteins to facilitate detailed investigations into its structure and function. By utilizing recombinant techniques, researchers can obtain purified forms of the protein, which are essential for exploring its interactions with other cellular components. This research paves the way for elucidating CEACAM19's role in cancer biology and its potential as a biomarker or therapeutic target. Overall, the study of CEACAM19 recombinant protein is an important avenue in understanding its physiological relevance and potential clinical applications in oncology.

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