Analytical Data
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Gene name
CSRP3
- Application
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Alternative Names
Cardiac LIM protein;Cysteine-rich protein 3 ;CRP3LIM domain protein, cardiacMuscle LIM protein
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P50461
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Expression Region
1-194aa
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Molecular Weight
37 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CSRP3 (Cysteine and Serine-rich Protein 3), also known as muscle LIM protein (MLP), plays a crucial role in muscle development and function, particularly in cardiac and skeletal muscles. It is associated with the structural integrity of the sarcomere, the fundamental unit of muscle contraction. Studies have shown that CSRP3 acts as a scaffold for signaling molecules and transcription factors, contributing to the regulation of gene expression and cellular responses to mechanical stress. Mutations in the CSRP3 gene have been linked to various cardiomyopathies, highlighting its importance in maintaining heart health. The recombinant protein form of CSRP3 is a valuable tool for investigating its molecular functions and interactions in vitro. Researchers aim to produce this protein through recombinant DNA technology for further studies, including structural analysis, protein-protein interactions, and functional assays. Understanding the precise role of CSRP3 in muscle signaling pathways can provide insights into the mechanisms underlying muscular diseases and lead to potential therapeutic strategies. As such, the development of CSRP3 recombinant protein is fundamental for advancing our knowledge of muscle biology and improving approaches to treat related disorders.
