Analytical Data
-
Gene name
Dct
- Application
-
Alternative Names
DOPAchrome conversion factor1 Publication DOPAchrome isomerase1 Publication DOPAchrome oxidoreductase1 Publication L-dopachrome Delta-isomerase SLATY locus protein Tyrosinase-related protein 2
-
Species
Mouse
-
Source
E. coli
-
Tag
N- His-SUMO & C- Myc
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P29812
-
Expression Region
24-472aa
-
Molecular Weight
71.2 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Dct (Dopachrome tautomerase) is an enzyme involved in the melanogenesis pathway, playing a crucial role in the production of melanin, which is responsible for pigmentation in various organisms. The study of Dct and its recombinant proteins has garnered significant interest due to its potential implications in various fields, including dermatology, cosmetics, and biotechnology. Researchers investigate Dct to better understand its function in melanin synthesis and its role in pigmentation disorders, such as vitiligo and albinism. Moreover, recombinant Dct proteins are being explored for their therapeutic applications, including skin protection against UV radiation and potential use in pigmentation treatments. By producing Dct through recombinant DNA technology, scientists can study its structural and functional properties in greater detail, enabling insights into its enzymatic mechanisms and interactions with other proteins in the melanin biosynthetic pathway. Additionally, the ability to produce large quantities of Dct allows for the exploration of its use in developing novel pigmentation agents or as a target for innovative treatments addressing hyperpigmentation or other related skin conditions. Thus, the investigation into Dct recombinant proteins reflects a multidisciplinary approach, combining molecular biology, biochemistry, and clinical research to unlock new possibilities in skin health and cosmetic science.
