Analytical Data
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Gene name
DCTD
- Application
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Alternative Names
dCMP deaminase
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P32321
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Expression Region
1-178aa
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Molecular Weight
47 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DCTD (deoxycytidine triphosphate deaminase) is an important enzyme involved in nucleotide metabolism, particularly in the deamination of dCTP to dUTP, thus playing a vital role in maintaining nucleotide pools and ensuring DNA integrity. Dysregulation of DCTD activity has been linked to various diseases, including cancer, where altered nucleotide metabolism can lead to increased mutation rates and genomic instability. Recent studies have highlighted the significance of DCTD in cellular processes such as DNA repair, replication, and overall cellular proliferation. As researchers aim to better understand the enzyme's structure and function, recombinant DCTD protein has become a focal point for investigation. The production of this protein through recombinant technology allows for detailed biochemical studies, including enzyme kinetics, substrate specificity, and interaction with other biomolecules. Furthermore, understanding DCTD’s role in disease mechanisms may pave the way for novel therapeutic strategies targeting nucleotide metabolism. Given its critical role in cell biology, ongoing research into DCTD and its recombinant forms is poised to contribute significantly to the fields of molecular biology, pharmacology, and cancer research.
