Analytical Data
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Gene name
FBXL18
- Application
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Alternative Names
F-box and leucine-rich repeat protein 18
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96ME1
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Expression Region
1-365aa
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Molecular Weight
56.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FBXL18, a member of the F-box protein family, plays a crucial role in the ubiquitin-proteasome system, which is essential for protein degradation and regulation of various cellular processes. Research has indicated that FBXL18 is involved in the cell cycle, apoptosis, and differentiation, making it a significant focus in cancer biology and developmental studies. Its unique structural features allow it to interact with specific substrates, leading to targeted ubiquitination and proteolysis. Recent studies have linked aberrant FBXL18 expression to various malignancies, suggesting its potential as a biomarker or therapeutic target. Understanding the molecular mechanisms underlying FBXL18's function may provide insights into tumorigenesis and other pathological conditions. Furthermore, the characterization of FBXL18 as a recombinant protein paves the way for further functional assays, allowing researchers to explore its interactions and regulatory pathways in detail. This research can enhance our understanding of cellular homeostasis and may lead to novel therapeutic strategies for diseases where FBXL18 is implicated.
