Analytical Data
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Gene name
GNPDA1
- Application
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Alternative Names
Glucosamine-6-phosphate deaminase 1 ;GNPDA 1 ;GlcN6P deaminase 1Oscillin
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P46926
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Expression Region
1-289aa
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Molecular Weight
36.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GNPDA1 (Glucosamine-6-phosphate deaminase 1) is an enzyme that plays a pivotal role in amino sugar metabolism and is crucial for maintaining cellular glucose homeostasis. Recent studies have highlighted its involvement in various biological processes, including the regulation of insulin signaling and potential links to metabolic disorders such as obesity and type 2 diabetes. GNPDA1's function in the conversion of glucosamine-6-phosphate to fructosamine-6-phosphate makes it essential for the proper functioning of the hexosamine biosynthetic pathway, which is critical for post-translational modifications of proteins. Furthermore, genetic variations in the GNPDA1 gene have been associated with increased susceptibility to metabolic diseases, making it a significant target for therapeutic interventions. Research into recombinant GNPDA1 protein aims to elucidate its structural properties and enzymatic mechanisms, potentially leading to the development of novel treatments for metabolic disorders. By producing and characterizing this recombinant protein, scientists can better understand its role in cellular metabolism and explore its potential as a biomarker or therapeutic target in metabolic syndrome and related diseases.
