Analytical Data
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Gene name
KRT38
- Application
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Alternative Names
Hair keratin, type I Ha8Keratin-38 ;K38
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O76015
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Expression Region
2-456aa
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Molecular Weight
66.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KRT38, part of the keratin family, is a type of intermediate filament protein primarily expressed in epithelial tissues. Recent research has highlighted its potential role in various cellular processes, including maintenance of tissue architecture, response to stress, and regulation of cellular differentiation. Abnormal expression of keratins, including KRT38, has been implicated in a range of pathological conditions, such as skin disorders and certain types of cancer. The study of KRT38 recombinant proteins has gained interest due to their potential use in biomarker development and therapeutic applications. By examining the structural and functional properties of KRT38, researchers aim to understand its specific roles in keratinocyte biology and how it may contribute to disease mechanisms. Furthermore, recombinant KRT38 could serve as a valuable tool for studying epithelial cell behavior in vitro, allowing for greater insights into wound healing, tumorigenesis, and regenerative medicine. As the understanding of KRT38's functions deepens, it may pave the way for novel diagnostic and therapeutic strategies targeting keratin-related diseases.
