Analytical Data
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基因名
MRPL54
- Application
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别名
39S ribosomal protein L54; 39S ribosomal protein L54 mitochondrial; 39S ribosomal protein L54 mitochondrial precursor ; L54mt; mitochondrial; mitochondrial ribosomal protein L54 ; MRP L54 ; MRP-L54; MRPL54; RM54_HUMAN
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6P161
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表达区间
15-138aa
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分子量
18.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPL54, a mitochondrial ribosomal protein of the large subunit, plays a crucial role in the mitochondrial protein synthesis process, which is essential for maintaining mitochondrial function and cellular energy metabolism. Research has shown that mutations or dysfunctions in MRPL54 can lead to mitochondrial diseases, contributing to a variety of disorders characterized by energy deficiency, including myopathies and neurodegenerative diseases. The study of MRPL54 recombinant protein has gained attention in the field of molecular biology and medicine, as understanding its structure and function could unveil the underlying mechanisms of mitochondrial translation and its implications in health and disease. Furthermore, recombinant MRPL54 can serve as a valuable tool for investigating mitochondrial ribosome assembly, translational regulation, and the interaction of mitochondrial proteins, paving the way for potential therapeutic strategies aimed at restoring mitochondrial function in affected patients. As researchers continue to explore the intricacies of MRPL54 and other mitochondrial ribosomal proteins, advancements in this area may lead to improved diagnosis and treatment options for mitochondrial disorders, underscoring the importance of this protein in both basic research and clinical applications.
