Analytical Data
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Gene name
PCOLCE2
- Application
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Alternative Names
Procollagen COOH-terminal proteinase enhancer 2 Short name: PCPE-2 Short name: Procollagen C-proteinase enhancer 2
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UKZ9
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Expression Region
24-415aa
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Molecular Weight
59.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PCOLCE2, or procollagen C-endopeptidase enhancer 2, is a key protein involved in the regulation of collagen synthesis and maturation, playing a crucial role in extracellular matrix (ECM) remodeling. Given its significant function in connective tissue biology, PCOLCE2 has garnered attention in the context of various diseases, including fibrotic disorders, cardiovascular diseases, and cancer. Research has demonstrated that alterations in PCOLCE2 expression can affect collagen deposition and ECM integrity, highlighting its potential as a therapeutic target. Additionally, understanding the molecular mechanisms underlying PCOLCE2 function can provide insights into tissue repair and regeneration processes. The production of recombinant PCOLCE2 proteins is essential for in-depth studies aimed at deciphering its role in collagen dynamics and the impact of its dysregulation in pathological conditions. This research not only seeks to elucidate the biochemical pathways associated with PCOLCE2 but also aims to explore its potential as a biomarker for disease progression or therapeutic response, paving the way for novel interventions in ECM-related diseases.
