Analytical Data
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基因名
TBCC
- Application
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别名
Tubulin-folding cofactor C ;CFC
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15814
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表达区间
2-345aa
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分子量
43 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of TBCC (tubulin-specific chaperone C) recombinant protein has garnered significant attention in recent years due to its crucial role in the assembly and regulation of tubulin, a key structural component of the cytoskeleton in eukaryotic cells. Tubulin polymerization into microtubules is essential for various cellular processes, including cell division, intracellular transport, and maintenance of cell shape. TBCC, as a chaperone, assists in the proper folding and assembly of tubulin, ensuring the formation of functional microtubules. Dysfunction in tubulin dynamics is associated with several diseases, including cancer and neurodegenerative disorders, highlighting the importance of understanding TBCC's mechanisms. Research on TBCC recombinant protein aims to elucidate its structure-function relationship, to explore its interactions with tubulin, and to investigate its potential as a therapeutic target. By producing TBCC in recombinant systems, researchers can study its biochemical properties in detail, facilitating the development of strategies to modulate its activity in pathological conditions. Ultimately, this research could pave the way for novel treatments that leverage the manipulation of microtubule dynamics to address various diseases linked to cytoskeletal dysfunction.
