Analytical Data
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基因名
TBPL1
- Application
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别名
21KDA TBP-like protein;Second TBP of unique DNA protein ;STUDTATA box-binding protein-related factor 2 ;TBP-related factor 2TBP-like factorTBP-related protein
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P62380
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表达区间
1-185aa
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分子量
36.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TBPL1, or TATA-box binding protein-like 1, is a member of the TBP family, which plays a pivotal role in the initiation of gene transcription by binding to the TATA box within promoter regions of DNA. Research on TBPL1 has gained momentum due to its potential implications in various biological processes and diseases, such as cancer and developmental disorders. Unlike its well-characterized counterpart TBP, TBPL1 exhibits distinct expression patterns and functional attributes, suggesting it may have specialized roles in regulating gene expression. Studies have indicated that TBPL1 may participate in alternative promoter usage and modulate the transcription of specific genes, thus impacting cellular differentiation and proliferation. Additionally, the involvement of TBPL1 in the regulation of non-coding RNAs has garnered interest, linking it to post-transcriptional mechanisms. Understanding the structure and functional dynamics of TBPL1 through recombinant protein studies could offer valuable insights into its mechanisms of action and biological significance. As such, the generation and characterization of recombinant TBPL1 protein are crucial for elucidating its role in transcriptional regulation and its potential as a therapeutic target in related disorders. Researchers are actively exploring the biochemical properties and interactions of TBPL1 to provide a clearer understanding of how it influences gene expression and cellular processes, paving the way for future studies aimed at developing novel interventions in diseases associated with TBPL1 dysregulation.
