Cat: IPD-X40017

Recombinant Human TEX12 Protein ,GST

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Analytical Data

  • Gene name

    TEX12

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Testis expressed gene 12; Testis expressed sequence 12 protein variant 3; Testis-expressed sequence 12 protein; TEX12; TEX12_HUMAN

  • Species

    Human

  • Source

    E. coli

  • Tag

    N- GST

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9BXU0

  • Expression Region

    1-123aa

  • Molecular Weight

    41.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TEX12 is a protein that has garnered significant interest in the field of molecular biology due to its potential roles in various cellular processes, including gametogenesis and early embryonic development. It is part of the TEX family of proteins, which are predominantly expressed in testicular tissues and are believed to play a crucial role in spermatogenesis and fertility. Research has indicated that TEX12 is involved in the formation of the synaptonemal complex during meiosis, mediating the pairing and recombination of homologous chromosomes. Abnormal expression or mutations in the TEX12 gene have been associated with male infertility and other reproductive disorders. Consequently, understanding the structure, function, and regulation of TEX12 is essential not only for elucidating the mechanisms underlying reproductive biology but also for developing potential therapeutic strategies for infertility. Recent advances in techniques such as CRISPR-Cas9 gene editing and high-throughput sequencing have opened new avenues for investigating the functional dynamics of TEX12 and its interactions with other proteins within the reproductive system. As researchers delve deeper into the functional repertoire of TEX12, the insights gained may contribute to the broader understanding of gene regulation during gamete formation and the implications for reproductive health.

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