Analytical Data
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Gene name
TIMM17A
- Application
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Alternative Names
Inner membrane preprotein translocase Tim17a
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q99595
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Expression Region
1-171aa
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Molecular Weight
45 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TIMM17A (Translocase of Inner Mitochondrial Membrane 17A) is a crucial protein involved in the transport of proteins into mitochondria, playing a significant role in mitochondrial function and integrity. Mitochondria, often referred to as the powerhouses of the cell, are essential for ATP production and regulating cellular metabolism, highlighting the importance of proper mitochondrial protein import. Research on TIMM17A has gained attention due to its implications in various diseases, including neurodegenerative disorders and metabolic syndromes, where mitochondrial dysfunction is a key factor. Understanding TIMM17A's structure, function, and interactions with other mitochondrial proteins is vital for unraveling the mechanisms underlying mitochondrial biogenesis and dynamics. Moreover, the development of TIMM17A recombinant proteins can serve as valuable tools for probing mitochondrial protein import pathways and identifying potential therapeutic targets for mitochondrial-related diseases. By studying TIMM17A, researchers aim to elucidate its role in mitochondrial homeostasis and its broader implications for cellular health, paving the way for innovative strategies to combat mitochondrial dysfunction.
